Skin Ceuticals Triple Lipid Restore 2-4-2

A patented ceramide cream that refills cellular lipids and restores the skin's moisture barrier to nourish dry skin.

Triple Lipid Restore 2:4:2 is a unique lipid cream containing the first 2:4:2 cholesterol-dominant ratio of 2% pure ceramides 1 and 3, 4% natural cholesterol, and 2% fatty acids, which is proven to refill skin lipids, hydrate skin and improve skin's barrier function to nourish dry skin and correct signs of aging such as smoothness, firmness, pores, and overall radiance.

Ingredients

Full ingredient list
Aqua/Water/Eau, Dimethicone, Hydrogenated Polyisobutene, Glycerin, Cholesterol, C12-15 Alkyl Benzoate, Ceramide 3, Helianthus Annuus Seed Oil Unsaponifiables, Bis-PEG-18 Methyl Ether Dimethyl Silane, Sodium Polyacrylate, PEG-10 Dimethicone, Nylon-12, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Dimethicone/PEG-10/15 Crosspolymer, Phenoxyethanol, Disteardimonium Hectorite, Hydroxyethylpiperazine Ethane Sulfonic Acid, Ammonium Polyacryloyldimethyl Taurate, Chlorphenesin, Caprylyl Glycol, PEG/PPG-18/18 Dimethicone, Propylene Carbonate, Disodium EDTA, Acrylonitrile/Methyl Methacrylate/Vinylidene Chloride Copolymer, Adenosine, Dipropylene Glycol, Lavandula Angustifolia Oil, Rosmarinus Officinalis Leaf Oil, t-Butyl Alcohol, Mentha Piperita Oil, Sodium Citrate, Linalool, Isobutane, Ceramide EOP, BHT, Tocopherol, Limonene.

Best for

Skin Ceuticals Triple Lipid Restore 2-4-2 is best for: All skin types

How to use

Dispense a small dab onto your fingertips and rub gently to soften the cream before smoothing it over the face, neck, and décolletage. Use once or twice a day. For morning routines, layer it over a SkinCeuticals vitamin C antioxidant serum and finish with a SkinCeuticals sunscreen; at night, if your routine includes a retinol, apply this cream as the following step.

Clinical Results

66%Improvement in smoothness
35%Improvement in skin laxity
20%Improvement in evenness
26%Improvement in radiance
44%Improvement in pore appearance
Protocol
Average results shown. A dermatologist-controlled 8-week clinical study on 55 subjects with twice daily application of Triple Lipid Restore 2:4:2. Subjects also used SkinCeuticals Gentle Cleanser and Ultimate UV Defense SPF 30. Inclusion Criteria: Females ages 55-75 with moderate fi ne lines/wrinkles, uneven skin tone, skin dullness, skin roughness, lack of skin tone clarity, and lack of skin firmness. Average results shown. Lipidomics analysis (N=28 females aged 55-75). Statistically significant increase in lipids determined by spectrometric analysis of tape strips collected at baseline and after 8 weeks of twice daily application of Triple Lipid Restore 2:4:2.

Product Images

Before & After

Before 1 After 1

Reviews

4.5 ★★★★★ 2898 reviews · as of August 2026
What SkinCeuticals customers report
  • Deep, all-day hydration
  • Luxurious texture that absorbs cleanly — no grease, no pilling
  • Visibly smoother, more youthful-looking skin
  • Gentle on sensitive and reactive skin, with no congestion

Reviews from SkinCeuticals, not BelleSkin customers.

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Total $318.00
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Skin Ceuticals Triple Lipid Restore 2-4-2
$190.00